Halogenation of Phenothiazines by Hydrogen HalideDimethyl Sulfoxide
نویسندگان
چکیده
منابع مشابه
Decarbonylative halogenation by a vanadium complex.
Metal-catalyzed halogenation of the C-H bond and decarbonylation of aldehyde are conventionally done in nature. However, metal-mediated decarbonylative halogenation is unknown. We have developed the first metal-mediated decarbonylative halogenation reaction starting from the divanadium oxoperoxo complex K3V(5+)2(O2(2-))4(O(2-))2(μ-OH) (1). A concerted decarbonylative halogenation reaction was p...
متن کاملDisinfection by-products from halogenation of aqueous solutions of terpenoids.
We report the formation of trihalomethanes and other disinfection by-products from four polyfunctional terpenoids during simulated chlorination of natural waters. Complex suites of products were identified by closed loop stripping analysis (CLSA)/gas chromatography-mass spectrometry (GC-MS) from halogenation of beta-carotene and retinol. beta-Ionone appeared to be a key intermediate in the halo...
متن کاملThe Halogenation of Aromatic Carbinols
In recent years many efforts have been made aiming to define the conditions of the reaction of substitution which lead to inversion of configuration (Walden inversion). The investigations in this direction of Polanyi et al.,’ of Olson,2 of Hughes, Ingold, et aL3 are most outstanding. Polanyi et al. and Olson came to the conclusion that all reactions of substitution by a negative group or ion ar...
متن کاملAntimicrobial activity of phenothiazines.
Multidrug-resistant Mycobacterium tuberculosis (MDRTB) and antibiotic-resistant Plasmodium falciparum are the major global lethal infections accounting for over 4 million deaths per year. Methicillin-resistant Staphylococcus aureus (MRSA) is the major global nosocomial infection and resistance to vancomycin is evident and may become common. This review provides the scientific and medical basis ...
متن کاملDimethyl sulfoxide prevents DNA nicking mediated by ionizing radiation or iron/hydrogen peroxide-generated hydroxyl radical.
Eighty percent of the single-strand DNA breaks induced by gamma-irradiation were prevented by the hydroxyl radical (.OH) scavenger dimethyl sulfoxide (Me2SO); CH4 was generated in the process as a product of the interaction of .OH and Me2SO. In contrast, Me2SO completely blocked DNA nicking by an iron/H2O2 system which produces .OH but smaller amounts of CH4 from Me2SO. Because Me2SO prevented ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Nippon kagaku zassi
سال: 1970
ISSN: 0369-5387,2185-0917
DOI: 10.1246/nikkashi1948.91.11_1075